T1rho MRI of Menisci and Cartilage in Osteoarthritic Patients at 3T
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چکیده
Introduction The loss of glycosaminoglycans (GAGs) and breakdown of collagen are typical characteristics of early osteoarthritis (OA) (1). T1rho mapping has been shown to be sensitive to changes in cartilage proteoglycan loss (2). Previous studies have demonstrated that cartilage T1rho values are elevated in OA patients compared to corresponding healthy subjects (3, 4). Recent work has reported (5, 6) that T1rho values of the meniscus and the adjacent cartilage varies in healthy subjects and OA patients. The aim of this study was to assess and compare the compartment-wise T1rho values of menisci and cartilage with doubtful (Kellgren-Lawrence (KL) grade 1) to severe (KL4) OA at 3T.
منابع مشابه
The relationship between T1rho measurements in the meniscus and cartilage in healthy subjects and patients with osteoarthritis
Meniscal damage has been shown to play a central role in the development and progression of osteoarthritis (OA). However, few studies have investigated the interrelationship between cartilage and meniscus using quantitative magnetic resonance imaging (MRI) measurements. The purpose of this study was to investigate the relationship between cartilage and meniscus and to determine which cartilage ...
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Introduction Prestructural characteristics of early osteoarthritis (OA) are the loss of glycosaminoglycans (GAG) and collagen breakdown (1). T1rho mapping has been shown to be sensitive to changes in cartilage proteoglycan loss (2). Previous studies have demonstrated that the T1rho values are elevated in OA patients when compared with corresponding healthy subjects (3, 4). Recently, it has been...
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تاریخ انتشار 2010